Domus Serafino
Piazza dell'Unità 24
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Why people book this hotel
“Gave us detailed information how to get to the location from the airport and det…”
“Great location in Prati close to Metro”
“The property was clean, the host was kind and let us leave our bags on the day o…”
“Very clean and comfortable”
“A special mention to Marco, who provided exceptional care and service from the s…”
“I second what others before me have said, Marco is an amazing host who's helped …”
“The apartment was spotless, spacious, and had everything we needed for a comfort…”
“It was nice we could leave our bags here before the room was ready to check in, …”
“Everything was very clean, with daily cleaning and good Wi-Fi”
Overview
Domus Serafino is located in the Vatican City - Prati district in Rome, 600 metres from Vatican Museums. Each room includes a flat-screen TV and is fitted with a private bathroom. For your comfort, you will find free toiletries and a hairdryer. Domus Serafino features free WiFi throughout the property. You will find a shared kitchen at the property. Castel Sant'Angelo is 700 metres from Domus Serafino, while The Vatican is 700 metres away. The nearest airport is Rome Ciampino Airport, 16 km from Domus Serafino.
Traveller reviews
Teodor
couple
June 19, 2026
The property was clean, the host was kind and let us leave our bags on the day of the checkout. Gave us detailed information how to get to the location from the airport and detailed information about the city.
Thihan
couple
June 15, 2026
“Great location to explore Rome. Would stay again.”
Great location in Prati close to Metro. Marco and Marco great communication and welcome. Very clean and comfortable.
Vicky
couple
June 14, 2026
“Excellent central location, clean and spacious accommodation, with outstanding care and service from Marco throughout ou”
We had a wonderful stay in Domus Serafino. The accommodation was in a fantastic central location, making it easy to explore all the major sights on foot or via Metro (which is only a few minutes walk). The apartment was spotless, spacious, and had everything we needed for a comfortable stay. Communal living space and kitchen with an espresso machine, large fridge and microwave. A special mention to Marco, who provided exceptional care and service from the second we booked to even after we left. He was incredibly helpful, attentive, and made us feel genuinely welcome. We would happily stay here again and highly recommend it to anyone visiting Rome.
Wai Bun
solo_traveller
June 14, 2026
Close to the Vantican Museum and the St. Peter's Basilica.
Dora
couple
June 14, 2026
“Lovely, clean room at an amazing location in Prati”
I second what others before me have said, Marco is an amazing host who's helped us every step of the way. It was nice we could leave our bags here before the room was ready to check in, and even after checkout before we had to head to the airport. The location in Prati is amazing: close to the metro, lots of restaurants around, and it's way more quiet than the city centre. You can get to the Vatican quickly, or even walk to the area of Piazza Navona in around 20 minutes. The room itself was very clean and comfortable with air conditioning and a private bathroom. We loved that there was an iron we could borrow and that we could put drinks and food in the fridge in the common area.
Denise
solo_traveller
June 6, 2026
Very clean and serviced well.
Elena
couple
June 4, 2026
The apartment was clean and reasonably comfortable for a short stay. The location was fine, and overall the accommodation itself was acceptable.
Tamas
couple
May 21, 2026
“A comfortable and relaxing stay in a beautiful location in Rome.”
Very clean, elegant apartment in a great location. The host was very very kind, and the check-in process was very easy. We felt great during our stay and would gladly come back.
Jackson
couple
May 5, 2026
Location, cleanliness and quiet
Abby
solo_traveller
April 19, 2026
We really enjoyed our stay at Domus Serafino. Marco was a brilliant host and very attentive and quick to respond to any queries. The guesthouse is in a lovely location near the Vatican. It was very quiet at night and felt a safe area. All major sites in Rome were in walking distance. The room was very clean, spacious and well maintained. We will look to rebook if we are back in Rome!
Emma
couple
February 23, 2026
The location is amazing! Perfect room size and overall fabulous place to stay
Connor
couple
February 23, 2026
“Fabulous really loved it”
The thing I liked about the property was located in a brilliant part of the city with a sort walk to nearby shops restaurants etc it was clean well maintained we got a warm welcome from the owner very helpful would recommend it and will be back in the near future
Bengü
couple
January 29, 2026
“I have a lovely home in Rome, anymore.”
Everything is great about Serafino. I just felt at home. And Now I say to myself I have a warm, lovely home in Rome. Marco is the owner of the guest house. He is very kind, helpful and friendly. The location, the apartment, the room, the living room is so comfortable and clean. Domus Serafino is one of the best part of our journey in Rome.
Jacquelyn
solo_traveller
January 19, 2026
“Very nice”
There was a lift, which was very helpful with luggage. Having a coffee machine and access to a fridge also great.
Christil Nsanya
couple
November 28, 2025
“The host was very lovely and let us check in early, great location, loved that there was coffee and tea provided!”
Great location, close to metro, buses and a short walk to St Peter’s square
Yavuz
couple
November 26, 2025
“Exceeded our expectations. Excellent stay.”
We had a very pleasant stay in Domus Serafino. Easy to reach from airport, close to many attractions, comfortable, clean, nice hosting. It is a six room flat each rented seperately. You need to be in contact with the host especially before your stay as they are not always in the premises. And a hint, the local restaurant just near the Domus Serafino building is an excellent choice for having a nice dinner. In summary, I strongly advise Domus Serafino.
Дмитрий
family_with_children
November 1, 2025
“Perfect location, very clean, and excellent service. We highly recommend this place.”
Great apartments in a quiet area, just a short walk from the old town, metro, and buses. There are lots of cafés, shops, and supermarkets nearby. Everything was very clean, with daily cleaning and good Wi-Fi. The staff were friendly, and Marco was always ready to help. We really recommend this place!
Jane
couple
October 25, 2025
“Ten minutes walk to all things Vatican in a vibrant area with good choice of restaurants”
Marco was an excellent host with prompt and useful answers to questions pre-stay. It was finished to a good standard, our deluxe room was spacious with comfortable bed and decent shower. We didn’t find any English news programmes on TV but actually that was a good thing.
Marialuisa
family_with_children
October 11, 2025
The host was very nice and the property was all renovated and clean
ShalJay
family_with_children
October 8, 2025
“Lovely stay in Rome”
Lovely building and welll appointed rooms. Lots of room which is rare for European hotels. The rooms were cleaned everyday which was great and tea/coffee facilities both in the room and the shared living room space was plentiful. Unfortunately a water pipe burst on the street which caused a water shortage but Marco did his best to top up the water in the hotel water tank and provide us with drinking water to manage the issue. Communication with Marco was easy and he was very responsive to our questions and provide great recommendations. The location was great with all the sites very walkable. Really enjoyed our stay and would stay again.
Facilities
Food & Drink
Breakfast options
General
Lift, Safety deposit box, Heating, Non-smoking rooms, Non-smoking throughout, Air conditioning, WiFi available in all areas
Internet
Internet services, WiFi, Free WiFi
Reception services
Invoice provided
Safety & security
Key access, Fire extinguishers
Deluxe Double Room
Providing free toiletries, this double room includes a private bathroom with a shower and a hairdryer. The air-conditioned double room provides a flat-screen TV, a private entrance, soundproof walls, a tea and coffee maker as well as city views. The unit offers 1 bed.
Double Room
Featuring free toiletries, this double room includes a private bathroom with a shower and a hairdryer. The air-conditioned double room features a flat-screen TV, a private entrance, soundproof walls, a tea and coffee maker as well as city views. The unit has 1 bed.
Standard Double Room
Providing free toiletries, this double room includes a private bathroom with a shower and a hairdryer. The air-conditioned double room provides a flat-screen TV, a private entrance, soundproof walls, a tea and coffee maker as well as city views. The unit offers 1 bed.
Hotel Policies
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