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Domus Serafino

Guest house

Piazza dell'Unità 24

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hotel

Why people book this hotel

Great location
15 mentions

Gave us detailed information how to get to the location from the airport and det…

Great location in Prati close to Metro

Clean rooms
15 mentions

The property was clean, the host was kind and let us leave our bags on the day o…

Very clean and comfortable

Friendly staff
13 mentions

A special mention to Marco, who provided exceptional care and service from the s…

I second what others before me have said, Marco is an amazing host who's helped …

Comfortable rooms
12 mentions

The apartment was spotless, spacious, and had everything we needed for a comfort…

It was nice we could leave our bags here before the room was ready to check in, …

Free Wi‑Fi
1 mentions

Everything was very clean, with daily cleaning and good Wi-Fi

Overview

Domus Serafino is located in the Vatican City - Prati district in Rome, 600 metres from Vatican Museums. Each room includes a flat-screen TV and is fitted with a private bathroom. For your comfort, you will find free toiletries and a hairdryer. Domus Serafino features free WiFi throughout the property. You will find a shared kitchen at the property. Castel Sant'Angelo is 700 metres from Domus Serafino, while The Vatican is 700 metres away. The nearest airport is Rome Ciampino Airport, 16 km from Domus Serafino.

Traveller reviews

T

Teodor

couple

June 19, 2026

10

The property was clean, the host was kind and let us leave our bags on the day of the checkout. Gave us detailed information how to get to the location from the airport and detailed information about the city.

T

Thihan

couple

June 15, 2026

9

Great location to explore Rome. Would stay again.

Great location in Prati close to Metro. Marco and Marco great communication and welcome. Very clean and comfortable.

V

Vicky

couple

June 14, 2026

10

Excellent central location, clean and spacious accommodation, with outstanding care and service from Marco throughout ou

We had a wonderful stay in Domus Serafino. The accommodation was in a fantastic central location, making it easy to explore all the major sights on foot or via Metro (which is only a few minutes walk). The apartment was spotless, spacious, and had everything we needed for a comfortable stay. Communal living space and kitchen with an espresso machine, large fridge and microwave. A special mention to Marco, who provided exceptional care and service from the second we booked to even after we left. He was incredibly helpful, attentive, and made us feel genuinely welcome. We would happily stay here again and highly recommend it to anyone visiting Rome.

W

Wai Bun

solo_traveller

June 14, 2026

9

Close to the Vantican Museum and the St. Peter's Basilica.

D

Dora

couple

June 14, 2026

10

Lovely, clean room at an amazing location in Prati

I second what others before me have said, Marco is an amazing host who's helped us every step of the way. It was nice we could leave our bags here before the room was ready to check in, and even after checkout before we had to head to the airport. The location in Prati is amazing: close to the metro, lots of restaurants around, and it's way more quiet than the city centre. You can get to the Vatican quickly, or even walk to the area of Piazza Navona in around 20 minutes. The room itself was very clean and comfortable with air conditioning and a private bathroom. We loved that there was an iron we could borrow and that we could put drinks and food in the fridge in the common area.

D

Denise

solo_traveller

June 6, 2026

10

Very clean and serviced well.

E

Elena

couple

June 4, 2026

6

The apartment was clean and reasonably comfortable for a short stay. The location was fine, and overall the accommodation itself was acceptable.

T

Tamas

couple

May 21, 2026

10

A comfortable and relaxing stay in a beautiful location in Rome.

Very clean, elegant apartment in a great location. The host was very very kind, and the check-in process was very easy. We felt great during our stay and would gladly come back.

J

Jackson

couple

May 5, 2026

9

Location, cleanliness and quiet

A

Abby

solo_traveller

April 19, 2026

10

We really enjoyed our stay at Domus Serafino. Marco was a brilliant host and very attentive and quick to respond to any queries. The guesthouse is in a lovely location near the Vatican. It was very quiet at night and felt a safe area. All major sites in Rome were in walking distance. The room was very clean, spacious and well maintained. We will look to rebook if we are back in Rome!

E

Emma

couple

February 23, 2026

10

The location is amazing! Perfect room size and overall fabulous place to stay

C

Connor

couple

February 23, 2026

10

Fabulous really loved it

The thing I liked about the property was located in a brilliant part of the city with a sort walk to nearby shops restaurants etc it was clean well maintained we got a warm welcome from the owner very helpful would recommend it and will be back in the near future

B

Bengü

couple

January 29, 2026

10

I have a lovely home in Rome, anymore.

Everything is great about Serafino. I just felt at home. And Now I say to myself I have a warm, lovely home in Rome. Marco is the owner of the guest house. He is very kind, helpful and friendly. The location, the apartment, the room, the living room is so comfortable and clean. Domus Serafino is one of the best part of our journey in Rome.

J

Jacquelyn

solo_traveller

January 19, 2026

8

Very nice

There was a lift, which was very helpful with luggage. Having a coffee machine and access to a fridge also great.

C

Christil Nsanya

couple

November 28, 2025

9

The host was very lovely and let us check in early, great location, loved that there was coffee and tea provided!

Great location, close to metro, buses and a short walk to St Peter’s square

Y

Yavuz

couple

November 26, 2025

8

Exceeded our expectations. Excellent stay.

We had a very pleasant stay in Domus Serafino. Easy to reach from airport, close to many attractions, comfortable, clean, nice hosting. It is a six room flat each rented seperately. You need to be in contact with the host especially before your stay as they are not always in the premises. And a hint, the local restaurant just near the Domus Serafino building is an excellent choice for having a nice dinner. In summary, I strongly advise Domus Serafino.

Д

Дмитрий

family_with_children

November 1, 2025

10

Perfect location, very clean, and excellent service. We highly recommend this place.

Great apartments in a quiet area, just a short walk from the old town, metro, and buses. There are lots of cafés, shops, and supermarkets nearby. Everything was very clean, with daily cleaning and good Wi-Fi. The staff were friendly, and Marco was always ready to help. We really recommend this place!

J

Jane

couple

October 25, 2025

9

Ten minutes walk to all things Vatican in a vibrant area with good choice of restaurants

Marco was an excellent host with prompt and useful answers to questions pre-stay. It was finished to a good standard, our deluxe room was spacious with comfortable bed and decent shower. We didn’t find any English news programmes on TV but actually that was a good thing.

M

Marialuisa

family_with_children

October 11, 2025

10

The host was very nice and the property was all renovated and clean

S

ShalJay

family_with_children

October 8, 2025

8

Lovely stay in Rome

Lovely building and welll appointed rooms. Lots of room which is rare for European hotels. The rooms were cleaned everyday which was great and tea/coffee facilities both in the room and the shared living room space was plentiful. Unfortunately a water pipe burst on the street which caused a water shortage but Marco did his best to top up the water in the hotel water tank and provide us with drinking water to manage the issue. Communication with Marco was easy and he was very responsive to our questions and provide great recommendations. The location was great with all the sites very walkable. Really enjoyed our stay and would stay again.

Facilities

Food & Drink

Breakfast options

General

Lift, Safety deposit box, Heating, Non-smoking rooms, Non-smoking throughout, Air conditioning, WiFi available in all areas

Internet

Internet services, WiFi, Free WiFi

Reception services

Invoice provided

Safety & security

Key access, Fire extinguishers

Deluxe Double Room

Providing free toiletries, this double room includes a private bathroom with a shower and a hairdryer. The air-conditioned double room provides a flat-screen TV, a private entrance, soundproof walls, a tea and coffee maker as well as city views. The unit offers 1 bed.

Max 2 guests 17 1 bedroom 1 bathroom
Double Room

Featuring free toiletries, this double room includes a private bathroom with a shower and a hairdryer. The air-conditioned double room features a flat-screen TV, a private entrance, soundproof walls, a tea and coffee maker as well as city views. The unit has 1 bed.

Max 2 guests 14 1 bedroom 1 bathroom
Standard Double Room

Providing free toiletries, this double room includes a private bathroom with a shower and a hairdryer. The air-conditioned double room provides a flat-screen TV, a private entrance, soundproof walls, a tea and coffee maker as well as city views. The unit offers 1 bed.

Max 2 guests 14 1 bedroom 1 bathroom

Hotel Policies

Check-inFrom 12:00 to 21:00
Check-outFrom 00:00 until 10:00
Cancellation & prepaymentCancellation and prepayment policies vary by room type. Please check your booking details before finalizing.
Accepted credit cardsThe hotel reserves the right to pre-authorise credit cards prior to arrival.
The fine printPlease inform in advance of your expected arrival time. You can use the Special Requests box when booking, or contact the property directly with the contact details provided in your confirmation. Guests are required to show a photo identification and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.
Last updated: Apr 11, 2024, 6:44 AM

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Domus Serafino - 3 Star Hotel in Rome